How to Lower Galectin-3
If you have been diagnosed with (or suspect yourself of having) health problems that affect your liver, gallbladder, and bile, then Galectin-3 is an inflammation biomarker that needs to get on your radar – and quick!
Galectin-3 is a type of protein that is secreted by your immune system when the body is fighting disease. These little molecules have anti-microbial properties that serve a protective function against harmful bacterial and fungal infections. Sounds like a positive, right?
Well yes, but…
Like most things, it’s the dose that determines the poison.
When your body is in homeostasis (i.e. optimal health), your Galectin-3 levels are also supporting your health.
But if your body is out of balance, elevated levels of Galectin-3 are both an indicator of, and a cause of, increased inflammation.
Think of Galectin-3 secretion as a self-reinforcing cycle that can send the body spinning into increasingly greater levels of pain, weight gain, and disease.
Recent studies have shown that Galectin-3 is a direct causative agent in a diverse range of diseases such as endometriosis, Alzheimer’s, and heart disease – and that Galectin-3 also plays a leading role in cancer progression.
Bringing it back to our friend, the liver …
Those with non-alcoholic fatty liver disease (NAFLD) need to be aware that elevated levels of Galectin-3 can provoke the escalation NAFLD to NASH, the more aggressive and dangerous non-alcoholic steatohepatitis (which is a precursor to cirrhosis and liver cancer).
The risk factors for progressing from NAFLD to liver cancer are even higher if you also have diabetes, high blood pressure, and/or obesity.
One of the ways to break the cycle of disease progression is to remove your excess circulating levels of Galectin-3 – thereby giving your body a chance to calm the inflammation and heal itself.
How can you lower Galectin-3 levels in the body?
Modified citrus pectin is derived from the pith of lemon, lime and orange peels. There is no juice of the fruit included, just the fluffy white padding from the inside of the citrus peel.
This pectin fiber is modified to a tiny size, which allows it to be absorbed through the walls of the intestines into the blood stream.
Once the pectin fiber enters the blood stream, it binds to and blocks Galectin-3, preventing it from wreaking further havoc in the body. This pesky protein is then filtered out of the blood through the body’s natural excretory processes.
PectaSol is the only clinically proven form of modified citrus pectin – which is why we offer it to our community!
With over 80+ peer-reviewed published studies and counting, PectaSol continues to gain recognition as a scientifically substantiated natural support for long-term health.
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Kram, Michael. “Galectin-3 inhibition as a potential therapeutic target in non-alcoholic steatohepatitis liver fibrosis.” World journal of hepatology vol. 15,2 (2023): 201-207. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011901/
Sciacchitano, Salvatore et al. “Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z.” International journal of molecular sciences vol. 19,2 379. 26 Jan. 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855601/